Authors: Dor Golomb, Amihay Nevo, Hanan Goldberg, Yaron Ehrlich, David Margel, David Lifshitz

Publication date: 2019/6/1

Journal: Journal of endourology

Volume: 33

Issue: 6

Pages: 469-474

Publisher: Mary Ann Liebert, Inc., publishers

:Description

• Purpose
  To reduce the high recurrence rate of nephrolithiasis, patients are routinely prescribed secondary chemoprevention therapy with alkali citrate (Alkasolve®; Sam-On Ltd) for uric acid stones and hypocitraturia or hydrochlorthiazide (Disothiazide®; Dexcel Ltd) for hypercalciuria. However, data on adherence to these regimens are limited. The aim of this study was to assess rates of long-term adherence to alkali citrate and hydrochlorothiazide and reasons for nonadherence.
• Materials and methods
  Patients on follow-up for kidney stone disease at a dedicated tertiary stone clinic, from 2010 to 2016, were asked to complete a telephone survey on adherence to secondary prevention medications and reasons for nonadherence. Compliance was also verified by actual drug distribution as reported through a computerized monitoring system.
• Results
  The cohort included 356 patients with mean age of 58 years, 199 …